End Stage of Kidney Disease Secondary to IgA Nephropathy
End stage of kidney disease or Uremia, means that your kidney damages are caused by the primary disease—IgA Nephropathy. Firstly, you should know Iga is a kind of auto-immune disease, it means the auto-immune system disordered. Every of us have IgA antibodies. For healthy people, it is normal reaction, but for patients with IgA disease, it is abnormal.
Too much immune complex is produced due to the abnormal immune response, such immune complex travel around the whole body along the bloodstream, called as circulatory immune complex, some of the immune complex deposit on the mesangial cells of the kidneys, causing the inflammation on the mesangial cells of the kidneys, so both the charge barrier and the mechanical barrier of the mesangial cells are injured, so the protein leak out into the urine.
Many doctors are suggested prednisone, Cyclosporine and or steroid for patients. Such medicines are often used to treat IgA Nephropathy, but it can't cure Iga, why? Such medicines only can stop the inflammation on the mesangial cells, but only remove that circulatory immune complex from the bloodstream, degrade that immune complex on the mesangial cells of the kidneys, stop inflammation response, and repair the injured mesangial cells of the kidneys simultaneously; such disease can be treated thoroughly.
You are now already on dialysis, which means your disease is not controlled in the early stage of IgA Nephropathy, it developed into end stage of kidney disease, then your doctor suggested kidney transplant for you, but have you considered that kidney transplant can help you get a new healthy kidney, but your primary disease, Iga, still exist, then the circulatory immune complex will deposit on the kidneys once again, the implanted kidney also will be injured then to failed, then do you have to do second Kidney Transplant after 6 or 7 years after the first Kidney Transplant.
Thereby, dialysis cannot be the cure for patients with end stage kidney disease secondary to IgA Nephropathy. If you have any question,please leave a message below or contact whatsapp+8618703318105
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